Amendments to planning permission dated 23rd January 2023 (RN: 22/05428/FULL) for two-storey extension including roof-level plant along the Bressenden Place façade to provide a new office entrance pavilion (Class E), the provision of Class E office / retail accommodation, remodelling of the crown of Portland House and creation of a setback rooftop extension to provide office amenity (Class E) and an outdoor terrace, reconfiguration of the second floor plant accommodation fronting Cardinal Place, relocation of the zephyr on Bressenden Place, provision of cycle parking, public realm and associated works including window replacement and the application of a new façade treatment, namely to amend the wording of Condition 3 (Code of Construction Practice) to enable early works to be carried out in accordance with the Appendix A dated 22/11/22 signed by the Environment Inspectorate and prior to the discharge of Condition 3.

Reserved Matters Approval of appearance, landscape, layout and scale for strategic green infrastructure, and the construction of a decked car park to support the Translational Office Space Project Building (TOSP), at the Genome Wellcome Campus (Outline reference: S/4329/18/OL) comprising: hard and soft landscape works, ecological mitigation and enhancement works; creation of pedestrian routes; tree removal and replacement and additional planting; provision of street furniture; construction of a decked car park including improvements to an existing access and pedestrian routes; drainage and utilities infrastructure; lighting, and all associated temporary construction operations, engineering works, demolition and groundworks and remodelling.